Deep brain stimulation (DBS) uses electrical pulses to stimulate an area of the brain. This can change the activity in that area of the brain. You may need two surgeries to implant the devices that stimulate the brain.
Most often, DBS is used to relieve symptoms of Parkinson's disease when they can't be controlled by medicines. But it can also be used for other conditions, such as obsessive-compulsive disorder and epilepsy.
The devices are often put in during separate surgeries on different days. Your doctor will drill small holes in your skull. Then tiny wire electrodes are placed in your brain. You may or may not be awake during the surgery. If you're awake, you will help the doctor know where to place the electrodes where they will work best. If you're not awake, your doctor might use a type of imaging (MRI) to help place the electrodes.
It may seem scary to be awake during this surgery. But your scalp will be numb. You won't feel any pain. You will stay in the hospital for a day or two after this surgery.
The other step is to put in a small, battery-powered generator. It's placed under the skin of your chest near your collarbone. This device is connected to the electrodes in your brain. To do this, the doctor will use a small wire that runs under your scalp and skin. You won't be awake for this surgery.
After the surgery, you will have a short hospital stay. Your doctor may wait for you to heal before turning on the generator.
What To Expect
You will stay in the hospital for a day or two after the procedure while your doctor checks the effect of DBS.
Why It Is Done
DBS may be used to relieve symptoms of Parkinson's disease, especially tremor, when they can't be controlled with medicine.
DBS of the thalamus is done to treat both disabling tremor caused by Parkinson's disease and essential tremor.
Procedures that stimulate parts of the brain called the subthalamic nucleus and the globus pallidus are done to help control a wider range of symptoms (along with tremor). They are used more often than stimulation of the thalamus. Symptoms that are most often helped (besides tremor) include problems with changes between "on" and "off" time and dyskinesia. "On" time is when medicine taken for Parkinson's is helping your symptoms. Symptoms that are less likely to get better include problems with walking, balance, and speech.
DBS may also be used to treat severe tremor related to multiple sclerosis (MS). It usually is a last resort after all other options have been tried without success to treat MS tremor. Only people with severe tremor are candidates.
How Well It Works
Compared with medicine alone, DBS combined with medicine may help increase “on” time. "On" time is when medicine taken for Parkinson's is helping your symptoms.
DBS that targets the thalamus is mainly used to treat tremor and does not work as well for other movement symptoms.
DBS that targets the subthalamic nucleus (STN) or globus pallidus internus (GPi) may help with a wider range of symptoms, including the difference in symptoms during “on” and “off” times and dyskinesia. Both approaches improve symptoms in similar ways, and quality of life is similar.
People who have DBS of the STN may be able to take less Parkinson’s medicine than those who have DBS of the GPi.
Risks
Risks of DBS include:
- Infection or skin irritation caused by the device in the chest (stimulator) or by the wires or electrodes.
- Bleeding in the brain during the surgery, resulting in a stroke.
- Numbness, tingling, twitching, or other abnormal sensations when the device is turned on. (These usually don't last long and can be stopped by adjusting the programming of the deep brain stimulation device.)
- Problems with the device, such as:
- A break in the wire leading from the electrode to the stimulator.
- Movement of the wires or the device under the skin.
- Need for a new battery for the device. A battery typically will last about 5 years.
- Failure or malfunction of the stimulator or the electrodes.
- Psychological problems, such as personality changes or depression.
- Problems with thinking, memory, speech, or swallowing.
- Trouble with walking or balance and an increased risk of falling.
- Seizures.
Credits
Current as of: February 27, 2026
Author: WebMD Ignite Staff
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